Start from Colorado (CO).
Hays, Kansas is stopping point #1 after driving about 380 miles (610 km) or 7.5 hours.
Kansas City, Missouri is stopping point #2 after driving about 270 miles (430 km) or 4 hours. Your total trip so far is about 640 miles or 1040 km over roughly 11.5 hours of driving.
Saint Charles, Missouri is stopping point #3 after driving about 230 miles (370 km) or 3.5 hours. Your total trip so far is about 870 miles or 1400 km over roughly 15 hours of driving.
Indianapolis, Indiana is stopping point #4 after driving about 260 miles (410 km) or 4 hours. Your total trip so far is about 1,130 miles or 1820 km over roughly 19.5 hours of driving.
Harrisburg, Pennsylvania is stopping point #5 after driving about 540 miles (870 km) or 9 hours. Your total trip so far is about 1,670 miles or 2690 km over roughly 28.5 hours of driving.
Finally, Delaware (DE) is your destination after driving about 120 miles (190 km) or 2.5 hours. Your total trip with all stops is around 1,790 miles or 2880 km, taking roughly 31.5 hours for the whole trip.