Your total trip with all stops is around 190 miles / 300 km, taking roughly 4 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between CLT and MYR.
Start from Charlotte Douglas International Airport.
Florence, South Carolina is stopping point #1 after driving about 120 miles (190 km) or 2.5 hours.
Finally, Myrtle Beach International Airport is your destination after driving about 70 miles (110 km) or 1.5 hours. Your total trip with all stops is around 190 miles or 300 km, taking roughly 4 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.