Drag the line on the map to calculate the driving distance for a different route.
The total driving distance from Sioux Falls, SD to Chicago, IL is 573 miles or 922 kilometers.
Your trip begins in Sioux Falls, South Dakota. It ends in Chicago, Illinois.
If you are planning a road trip, you might also want to calculate the total driving time from Sioux Falls, SD to Chicago, IL so you can see when you'll arrive at your destination.
You can also calculate the cost of driving from Sioux Falls, SD to Chicago, IL based on current local fuel prices and an estimate of your car's best gas mileage.
Since this is a long drive, you might want to stop halfway and stay overnight in a hotel. You can find the city that is halfway between Sioux Falls, SD and Chicago, IL.
Planning to fly a plane instead? You might be more interested in calculating the straight line distance to fly from Sioux Falls, SD to Chicago, IL.