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The total driving distance from Saint Louis, MO to Washington, DC is 818 miles or 1 316 kilometers.
Your trip begins in Saint Louis, Missouri. It ends in Washington, District of Columbia.
If you are planning a road trip, you might also want to calculate the total driving time from Saint Louis, MO to Washington, DC so you can see when you'll arrive at your destination.
You can also calculate the cost of driving from Saint Louis, MO to Washington, DC based on current local fuel prices and an estimate of your car's best gas mileage.
Since this is a long drive, you might want to stop halfway and stay overnight in a hotel. You can find the city that is halfway between Saint Louis, MO and Washington, DC.
Planning to fly a plane instead? You might be more interested in calculating the straight line distance to fly from Saint Louis, MO to Washington, DC.