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The total driving distance from Pittsburgh, PA to Wilkes-Barre, PA is 265 miles or 426 kilometers.
Your trip begins in Pittsburgh, Pennsylvania. It ends in Wilkes-Barre, Pennsylvania.
If you are planning a road trip, you might also want to calculate the total driving time from Pittsburgh, PA to Wilkes-Barre, PA so you can see when you'll arrive at your destination.
You can also calculate the cost of driving from Pittsburgh, PA to Wilkes-Barre, PA based on current local fuel prices and an estimate of your car's best gas mileage.
If you're meeting a friend, you might be interested in finding the city that is halfway between Pittsburgh, PA and Wilkes-Barre, PA.
Planning to fly a plane instead? You might be more interested in calculating the straight line distance to fly from Pittsburgh, PA to Wilkes-Barre, PA.