Drag the line on the map to calculate the driving distance for a different route.
The total driving distance from Kirksville, MO to Saint Louis, MO is 214 miles or 344 kilometers.
Your trip begins in Kirksville, Missouri. It ends in Saint Louis, Missouri.
If you are planning a road trip, you might also want to calculate the total driving time from Kirksville, MO to Saint Louis, MO so you can see when you'll arrive at your destination.
You can also calculate the cost of driving from Kirksville, MO to Saint Louis, MO based on current local fuel prices and an estimate of your car's best gas mileage.
If you're meeting a friend, you might be interested in finding the city that is halfway between Kirksville, MO and Saint Louis, MO.
Planning to fly a plane instead? You might be more interested in calculating the straight line distance to fly from Kirksville, MO to Saint Louis, MO.